Sodium Butyrate CAS 156-54-7

Sodium Butyrate Overview

Sodium Butyrate is a short-chain fatty acid salt derived from n-butyric acid. In the animal gastrointestinal tract, it serves as the primary energy source for colon epithelial cells, supporting mucosal repair, maintaining gut barrier integrity and exerting selective antimicrobial activity against enteric pathogens. It is widely recognized as a core functional ingredient in antibiotic-free livestock feeding programs.

Beyond nutrition uses, sodium butyrate inhibits mold and spoilage bacteria to extend shelf life in feed and food products. It also acts as a building block in pharmaceutical synthesis and a crosslinking modifier in resin production. UATChem produces sodium butyrate via refined synthetic processes, with tight control over free butyric acid and moisture content. The product has good flowability and low caking tendency, and is available in both standard grade and coated sustained-release grades for different intestinal release needs.

Primary Applications

Livestock nutrition
Added to swine, poultry and ruminant diets to support intestinal health. It fuels colonocytes, promotes villi development, reduces post-weaning diarrhea, improves nutrient absorption and supports growth performance, making it a key component in antibiotic-free feeding strategies.

Food & feed preservation
Inhibits the growth of mold and pathogenic bacteria in feed, silage and pet food products, extending shelf life. It also contributes to mild flavor modulation in formulated products.

Fine chemical & resin production
Used as an intermediate in the synthesis of butyric acid derivatives, and as a crosslinking stabilizer in resin manufacturing to improve water resistance and structural stability of polymer materials.

Technical Specifications

Storage and Handling

Store in tightly sealed packaging in a cool, dry environment at 5–30 °C. Keep away from strong acids and oxidizing agents to prevent moisture absorption, caking and volatilization of free butyric acid.

Dust may cause respiratory and eye irritation. Wear standard dust masks and safety goggles during bulk handling.

UATChem offers sodium butyrate in 25 kg PE-lined woven bags and 500 kg jumbo bags, with custom packaging available upon request. The product is classified as Non-DG for standard transport. Verify purity, moisture and free acid content upon receipt.

Frequently Asked Questions

Q: What is the difference between standard and coated sodium butyrate?

A: Standard grade dissolves quickly in the upper gut with a characteristic butyric odor, suitable for proximal gut conditioning. Coated grade is lipid-encapsulated for sustained release in the hindgut, with less odor and longer-lasting effect, ideal for young livestock.

Q: What is the typical dosage in weanling pig feed?

A: Standard grade is typically added at 1–3 kg per ton of complete feed. Coated grade is dosed based on active butyrate content. Adjust according to diet composition, production stage and health status.

Q: Does caking affect the efficacy of sodium butyrate?

A: Soft, easily crushed lumps do not impact active content. Severe caking with rancid odor indicates partial degradation. Store sealed and dry, and use opened bags promptly to maintain performance.