D-Mannose CAS 3458-28-4

D-Mannose (CAS 3458-28-4) is a white, sweet crystalline simple sugar that dissolves readily in water and occurs naturally in fruit. Commercial material is made by enzymatic conversion rather than animal sources, so it suits vegan and non GMO supplement and food lines. The largest outlet is urinary tract and bladder health powders, capsules and blends, often paired with cranberry. It also goes into functional food and drinks, pet and animal feed, cell culture media for controlled glycosylation and fine synthesis. The crystals are mildly hygroscopic. UATChem supplies food and supplement grade D-mannose in 25 kg paper bags or fiber drums and bulk bags; send the grade, quantity and destination for a quote with COA and SDS.

  • CAS: 3458-28-4
  • EC Number: 222-392-9
  • Synonyms: D-(+)-Mannose; D-mannopyranose
  • Molecular Formula: C₆H₁₂O₆
  • Molecular Weight: 180.16
  • Appearance: White to off-white crystalline powder
  • Melting Point: About 133 °C (alpha form)
  • Optical Rotation: [α]20/D about +14° (equilibrated, in water)
  • Solubility: Freely soluble in water; slightly soluble in ethanol
  • Source: Enzymatic, vegan, non GMO monosaccharide
  • Use: Urinary supplements, functional food, cell culture, feed
  • Packaging: 25 kg paper bag / fiber drum; FIBC, custom packing available
Get a Quote COA, SDS, packaging & CIF price within 1 hour
Category:

What D-Mannose Is

D-mannose is a six carbon reducing sugar and a C2 epimer of glucose, sold as a white to off-white crystalline powder with a clean, mild sweetness. It is present in small amounts in fruit, and commercial volumes are produced by enzymatic conversion of plant derived glucose, giving a vegan, non GMO material without animal inputs. The powder dissolves freely in water, exists as alpha and beta anomers and is mildly hygroscopic. Food and supplement buyers select it by grade and physical form rather than by a single assay, with identity confirmed by melting point and optical rotation. UATChem supplies food and supplement grade D-mannose, with assay, loss on drying and particle size reported on the COA for each lot, and trial quantities are available for formulation work.

Urinary Supplements, Food and Biotech Use

  • Urinary tract supplements. The leading outlet, used in urinary and bladder health powders, capsules and blends, often combined with cranberry or probiotic ingredients.
  • Functional food and drinks. A low sugar functional sweetener and nutrition ingredient for beverages, confectionery and fortified food products.
  • Biotech and cell culture. A cell culture medium component that channels into N-linked glycosylation to shape the glycan profile of therapeutic antibodies and recombinant proteins.
  • Feed and synthesis. Pet and young animal urinary and gut health feed, plus mannitol, drug glycosylation and vitamin synthesis.

Brands running several sugar based formulas also source fermented D-ribose for energy and sports nutrition lines.

Typical Specifications

Food and supplement grades differ in assay, loss on drying and particle size; values are reported on the COA for each lot, and the physical constants below identify the material.

Parameter Typical Value
Appearance White to off-white crystalline powder
Melting Point About 133 °C (alpha form)
Optical Rotation [α]20/D about +14° (equilibrated, water)
Solubility Freely soluble in water; slightly in ethanol
Source Enzymatic, vegan, non GMO
Form Powder or granules; food / supplement grade, COA per lot

Packaging, Documents and Ordering

  • Packed in food grade lined 25 kg paper bags or fiber drums and in 500 kg FIBC bulk bags; packs stay sealed, dry, cool and moisture protected, away from strong oxidizers, since the crystals are hygroscopic.
  • D-mannose is a food sugar safe within normal use and essentially non-toxic, with standard dust control for combustible powder handling. Every lot carries a COA with assay, loss on drying, particle size and optical rotation, together with TDS and SDS, and food compliance, allergen or non GMO statements and samples can be discussed at inquiry.
  • For a quote, UATChem needs the grade (food, supplement or reagent), form (powder or granules), quantity, packing and destination port.

FAQ

Q: What is D-mannose used for?

A: It is best known as a urinary tract health supplement ingredient, and also used in functional food, pet feed and cell culture.

Q: Is D-mannose vegan and non GMO?

A: Yes, it is made by enzymatic conversion of plant glucose with no animal inputs, giving vegan and non GMO supplement material.

Q: How is D-mannose different from glucose?

A: It is a six carbon sugar and a C2 epimer of glucose, mildly sweet and highly soluble in water, sold as a crystalline powder.

Ready to Source? Talk to Our Engineers

Industrial Chemical Raw Materials, Factory-Direct — Quote Within 1 Hour

Stable high-purity supply, flexible packaging and complete compliance documentation for your formulations — exporting worldwide since 2006.

  • 1000+Products
  • 200+QC Protocols
  • 7–15Days Delivery
  • Factory-Direct Pricing
  • COA / TDS / SDS Included
  • Free Samples for Testing
  • ISO 9001 Certified